Seite - (000013) - in Biomedical Chemistry: Current Trends and Developments

3.3.2.1 SP1-7 and its Binding Site 3.3.2.2 SAR and Truncation Studies of SP1–7 and EM-2 3.3.2.2.1 Strategy 3.3.2.2.2 Structure–activity Relationship 3.3.2.2.3 Effects of SP1–7 and its Analogs 3.3.2.3 Design and Synthesis of Small Constrained H-Phe-Phe- NH2 Analogs 3.3.2.3.1 Strategy 3.3.2.3.2 Structure–activity relationship and ADME properties 3.3.3 Conclusion References 3.4 Synthetic Vs. Natural Bioactive Compounds Against Tropical Disease 3.4.1 Introduction 3.4.2 Early History of Malaria Treatment; Quinine and Artemisinin 3.4.3 Post World War II and the Development of Synthetic Anti- malarials 3.4.4 Modern Efforts in Antimalarial Drug Development 3.4.4.1 Quinine, 4-Aminoquinolines, and Quinoline Methanols 3.4.4.2 8-Aminoquinolines 3.4.4.3 Artemisinins and other Endoperoxides 3.4.4.4 Repurposed Drugs