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Biomedical Chemistry: Current Trends and Developments
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dependent pathway”, European Journal of Medicinal Chemistry, 46, 2141-2146. Graczyk, P. P. (1999). Caspase inhibitors - A chemist’s perspective. Restorative Neurology and Neuroscience, 14(1), 1-23. Hanzlik, R. P., & Thompson, S. A. (1984). Vinylogous Amino-acid Esters - A New Class of Inactivators for Thiol Proteases. Journal of Medicinal Chemistry, 27(6), 711-712. Hayden, F. G., Turner, R. B., Gwaltney, J. M., Chi-Burris, K., Gersten, M., Hsyu, P., Patick, A. K., Smith, G. J., & Zalman, L. S. (2003). Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers. Antimicrobial Agents and Chemotherapy, 47(12), 3907-3916. Johansson, M. H. (2012). Reversible Michael Additions: Covalent Inhibitors and Prodrugs. Mini- Reviews in Medicinal Chemistry, 12(13), 1330-1344. Kathman, S. G., Xu, Z., & Statsyuk, A. V. (2014). A Fragment-Based Method to Discover Irreversible Covalent Inhibitors of Cysteine Proteases. Journal of Medicinal Chemistry, 57, 4969-4974. Kerr, I. D., Lee, J. H., Farady, C. J., Marion, R., Rickert, M., Sajid, M., Pandey, K. C., Caffrey, C. R., Legac, J., Hansell, E., McKerrow, J. H., Craik, C. S., Rosenthal, P. J., & Brinen, L. S. (2009). Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design. Journal of Biological Chemistry, 284(38), 25697-25703. Krishnan, S., Miller, R. M., Tian, B., Mullins, R. D., Jacobson, M. P., & Taunton J. (2014). Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis. Journal of the American Chemical Society, 136, 12624−12630. Kumar, S. P., Glória, P. M. C., Gonçalves, L. M., Gut, J., Rosenthal, P. J., Moreira, R., & Santos, M. M. M. (2012). Squaric acid: a valuable scaffold for developing antimalarials?, MedChemCommun, 3, 489-493. Liu, S., & Hanzlik, R. P. (1992). Structure-activity-relationships for Inhibition of Papain by Peptide Michael Acceptors. Journal of Medicinal Chemistry, 35(6), 1067-1075. Lucas, S. D., Costa, E., Guedes, R. C., & Moreira, R. (2013) Targeting COPD: Advances on low- molecular-weight inhibitors of human neutrophil elastase. Medicinal Research Reviews, 33, E73-E101 McGrath, M. E., Eakin, A. E., Engel, J. C., McKerrow, J. H., Craik, C. S., & Fletterick, R. J. (1995). The Crystal-structure of Cruzain - A Therapeutic Target for Chagas-disease. Journal of Molecular Biology, 247(2), 251-259. Meunier, B. (2008). Hybrid molecules with a dual mode of action: Dream or reality? Accounts of Chemical Research, 41, 69-77. Miller, R. M., Paavilainen, V. O., Krishnan, S., Serafimova, I. M., & Taunton, J. (2013). Electrophilic fragment-based design of reversible covalent kinase inhibitors. Journal of the American Chemical Society, 135, 5298-5301. Oliveira, R., Newton, A. S., Guedes, R. C., Miranda, D., Amewu, R. K., Srivastava, A., Gut, J., Rosenthal, P. J., O’Neill, P. M., Ward, S. A., Lopes, F., & Moreira, R. (2013). An Endoperoxide- based Hybrid Approach to Deliver Falcipain Inhibitors Inside Malaria Parasites. ChemMedChem, 8, 1528-1536. Oliveira, R., Guedes, R. C., Meireles, P., Albuquerque, I. S., Gonçalves, L. M., Pires, E., Bronze, M. R., Gut, J., Rosenthal, P. J., Prudêncio, M., Moreira, R., O’Neill, P., & Lopes, F. (2014).
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Biomedical Chemistry: Current Trends and Developments
Titel
Biomedical Chemistry: Current Trends and Developments
Autor
Nuno Vale
Verlag
De Gruyter Open Ltd
Datum
2016
Sprache
englisch
Lizenz
CC BY-NC-ND 4.0
ISBN
978-3-11-046887-8
Abmessungen
21.0 x 29.7 cm
Seiten
427
Schlagwörter
Physical Sciences, Engineering and Technology, Chemistry, Organic Chemistry, Green Chemistry
Kategorien
Naturwissenschaften Chemie
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Biomedical Chemistry: Current Trends and Developments