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Biomedical Chemistry: Current Trends and Developments
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and validation of automated SPE-HPLC-MS/MS methods for the quantification of asenapine, a new antipsychotic agent, and its two major metabolites in human urine. Biomedical Chromatography, 26(12), 1461-1463. Burton, P.S., Goodwin, J.T. (2010) Solubility and Permeability Measurement and Applications in Drug Discovery. Combinatorial Chemistry & High Throughput Screening, 13(2), 101-111. Carlson, T.J., Fisher, M.B., (2008) Recent Advances in High Throughput Screening for ADME Properties. Combinatorial Chemistry & High Throughput Screening, 11, 258-264. Cai, H., Verschoyle, R.D., Steward, W.P., Gescher, A.J., (2003) Determination of the flavone tricin in human plasma by high-performance liquid chromatography. Biomedical Chromatography, 17(7), 435-439. Chen, D., Lal, R., Zomorodi, K., Atluri, H., Ho, J., Luo, W., Tovera, J., Bonzo, D., Cundy, K., (2012) Evaluation of Gabapentin Enacarbil on Cardiac Repolarization: A Randomized, Double-Blind, Placebo- and Active-Controlled, Crossover Thorough QT/QTc Study in Healthy Adults. Clinical Therapeutics, 34(2), 351-362. Cheung, B.W., Cartier, L.L., Russlie, H.Q., Sawchuk, R.J., (2005) The application of sample pooling methods for determining AUC, AUMC and mean residence times in pharmacokinetic studies. Fundamental & Clinical Pharmacology, 19(3), 347-354. Chien, J.Y., Friedrich, S., Heathman, M.A., de Alwis, D.P., Sinha, V., (2005) Pharmacokinetics/Pharmacodynamics and the Stages of Drug Development: Role of Modeling and Simulation. AAPS Journal, 7(3), E544-559. Chhonker, Y.S., Chandasana, H., Kumar, D., Mishra, S.K., Srivastava, S., Balaramnavar, V.M., Gaikwad, A.N., Kanojiya, S., Saxena, A.K., Bhatta, R.S., (2014) Pharmacokinetic and metabolism studies of rohitukine in rats by high performance liquid-chromatography with tandem mass spectrometry. Fitoterapia, 97, 34-42. Cundy, K.C., Branch, R., Chernov-Rogan, T., Dias, T., Estrada, T., Hold, K., Koller, K., Liu, X., Mann, A., Panuwat, M., Raillard, S.P., Upadhyay, S., Wu, Q.Q., Xiang, J.N., Yan, H., Zerangue, N., Zhou, C.X., Barrett, R.W., Gallop, M.A., (2004) XP13512 [(+/-)-1-([(alpha- Isobutanoyloxyethoxy) carbonyl] aminomethyl)-1-cyclohexane Acetic Acid], A Novel Gabapentin Prodrug: I. Design, Synthesis, Enzymatic Conversion to Gabapentin, and Transport by Intestinal Solute Transporters. Journal of Pharmacology and experimental therapeutics, 311(1), 315-323. Di, L., Kerns, E.H., Ma, X.J., Huang, Y., Carter, G.T., (2008) Applications of High Throughput Microsomal Stability Assay in Drug Discovery. Combinatorial Chemistry & High Throughput Screening, 11(6), 469-476. Duff, G. (2007) Guidelines for phase 1 clinical trials. In: The Association of the British Pharmaceutical Industry, London, Association of the British Pharmaceutical Industry (pp. 1- 49). Eerkes, A., Shou, W.Z., Naidong, W., (2003) Liquid/liquid extraction using 96-well plate format in conjunction with hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the analysis of fluconazole in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 31(5), 917-928. EMA, Note for guidance on toxicokinetics: a guidance for assessing systemic exposure in toxicology studies (CPMP/ICH/384/95). EMA (1998) Note for Guidance of General considerations for clinical trials (CPMP/ICH/291/95). EMA (2004a) Guideline on pharmacokinetics of medicinal products in patients with impaired
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Biomedical Chemistry: Current Trends and Developments
Titel
Biomedical Chemistry: Current Trends and Developments
Autor
Nuno Vale
Verlag
De Gruyter Open Ltd
Datum
2016
Sprache
englisch
Lizenz
CC BY-NC-ND 4.0
ISBN
978-3-11-046887-8
Abmessungen
21.0 x 29.7 cm
Seiten
427
Schlagwörter
Physical Sciences, Engineering and Technology, Chemistry, Organic Chemistry, Green Chemistry
Kategorien
Naturwissenschaften Chemie
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Biomedical Chemistry: Current Trends and Developments