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Biomedical Chemistry: Current Trends and Developments
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Tsume, Y.; Hilfinger, J. M.; Amidon, G. L. (2008). Enhanced cancer cell growth inhibition by dipeptide prodrugs of Floxuridine: increase transporter affinity and metabolic stability. Molecular Pharmaceutics, 5, 717-727. Turanov, A. A.; Xu, X. M.; Carlson, B. A. Yoo, M. H.; Gladyshev, V. N.; Hatfield, D. L. (2011). Biosynthesis of selenocysteine, the 21st amino acid in the genetic code, and a novel pathway for cysteine biosynthesis. Advances in Nutrition, 2, 122-128. Turk, B. E.; Huang, L. L.; Piro, E. T.; Cantley, L. C. (2001). Determination of protease cleavage site motifs using mixture-based oriented peptide libraries. Nature Biotechnology 19, 661-667. Umapathy, N. S.; Ganapathy, V.; Ganapathy, M. E. (2004). Transport of amino acid esters and the amino-acid-based prodrug valganciclovir by the amino acid transporter ATB(0,+). Pharmaceutical Research, 21, 1303-1310. Vale, N.; Moreira, R.; Gomes, P. (2005). Quimioterapia da Malária: um século de desenvolvimento de antimaláricos. Química, 99, 57-69. Vale, N.; Collins, M. S.; Gut, J.; Ferraz, R.; Rosenthal, P. J.; Cushion, M. T.; Moreira, R.; Gomes, P. (2008a). Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones. Bioorganic and Medicinal Chemistry Letter, 18, 485-488. Vale, N.; Matos, J.; Gut, J.; Nogueira, F.; Rosário, V.; Rosenthal, P. J.; Moreira, R.; Gomes, P. (2008b). Imidazolidin-4-one peptidomimetic derivatives of primaquine: synthesis and antimalarial activity. Bioorganic and Medicinal Chemistry Letter, 18, 4150-4153. Vale, N.; Matos, J.; Moreira, R.; Gomes, P. (2008c). Amino acids as selective acylating agents: regioselective N1-acylation of imidazolidin-4-one derivatives of the antimalarial drug primaquine. Tetrahedron, 64, 11144-11149. Vale, N.; Nogueira, F.; do Rosário, V. E.; Gomes, P.; Moreira, R. (2009a). Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs. European Journal of Medicinal Chemistry, 44, 2506-2516. Vale, N.; Prudêncio, M.; Marques, C. A.; Collins, M.; Gut, J.; Nogueira, F.; Matos, J.; Rosenthal, P. J.; Cushion, M. T.; do Rosário, V. E.; Mota M. M.; Moreira, R.; Gomes, P. (2009b). Imidazoquines as antimalarial and antipneumocystis agents. Journal of Medicinal Chemistry, 52, 7800-7807. Vale, N.; Aguiar, L.; Gomes, P. Antimicrobial peptides: a new class of antimalarial drugs? (2014). Frontiers in Pharmacology, 5, 275. Vale, N.; Ferreira, A.; Fernandes, I.; Mateus, N.; Gomes, P. (2016). New peptide-gemcitabine conjugates for Cancer Therapy. (Submitted). Veber, D. F.; Johnson, S. R.; Cheng, H. Y.; Smith, B. R.; Ward, K. W.; Kopple, K. D. (2002). Molecular properties that influence the oral bioavailability of drug candidates. Journal of Medicinal Chemistry, 45, 2615-2623. Vig, B. S.; Lorenzi, P. J.; Mittal, S.; Landowski, C. P.; Shin, H. C.; Mosberg, H. I.; Hilfinger, J. M.; Amidon, G. L. (2003). Amino acid ester prodrugs of floxuridine: synthesis and effects of structure, stereochemistry, and site of esterification on the rate of hydrolysis. Pharmaceutical Research, 20, 1381-1388. Vig, B. S.; Lorenzi, P. L.; Mittal, S.; Landowski, C. P.; Shin, H-C.; Mosberg, H. I.; Hilfinger, J. M.; Amidon, G. L. (2003). Amino acid ester prodrugs of Floxuridine: synthesis and effects of structure, stereochemistry and site of esterification on the rate of hydrolysis. Pharmaceutical Research, 20, 1381-1388.
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Biomedical Chemistry: Current Trends and Developments
Titel
Biomedical Chemistry: Current Trends and Developments
Autor
Nuno Vale
Verlag
De Gruyter Open Ltd
Datum
2016
Sprache
englisch
Lizenz
CC BY-NC-ND 4.0
ISBN
978-3-11-046887-8
Abmessungen
21.0 x 29.7 cm
Seiten
427
Schlagwörter
Physical Sciences, Engineering and Technology, Chemistry, Organic Chemistry, Green Chemistry
Kategorien
Naturwissenschaften Chemie
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Biomedical Chemistry: Current Trends and Developments