Seite - (000325) - in Biomedical Chemistry: Current Trends and Developments

a The results are expressed as mean ± SD. b Papp = apparent permeability coefficient. c a–b = apical to basolateral. d b–a = basolateral to apical. References Anthes, J. C., Chapman, R. W., Richard, C., et al. (2002). SCH 206272: a potent, orally active tachykinin NK1, NK2, and NK3 receptor antagonist. European Journal of Pharmacology, 450(2), 191-202. Bergström, C. A. S., Strafford, M., Lazorova, L., et al. (2003). Absorption classification of oral drugs based on molecular surface properties. Journal of Medicinal Chemistry, 46(4), 558- 570. Berman, H. M., Westbrook, J., Feng, Z., et al. (2000). The Protein Data Bank. Nucleic Acids Research, 28(1), 235-242. Boden, P., Eden, J. M., Hodgson, J., et al. (1994). The rational development of small molecule tachykinin NK3 receptor selective antagonists - the utilization of a dipeptide chemical library