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Cooperet al. Nanoparticles for radiation therapy cancer radiation therapy and imaging.Adv. Funct.Mater. 24, 1718–1729. doi: 10.1002/adfm.201302312 Zhang,X.D.,Guo,M.L.,Wu,H.Y.,Sun,Y.M.,Ding,Y.Q.,Feng,X., etal. (2009). Irradiationstabilityandcytotoxicityofgoldnanoparticles forradiotherapy. Int. J.Nanomedicine4,165–173.doi:10.2147/IJN.S6723 Zhang, X. D., Wu, D., Shen, X., Chen, J., Sun, Y. M., Liu, P. X., et al. (2012). Size-dependent radiosensitization of PEG-coated gold nanopar- ticles for cancer radiation therapy. Biomaterials 33, 6408–6419. doi: 10.1016/j.biomaterials.2012.05.047 Conflict of Interest Statement:The authors declare that the research was con- ducted in the absence of any commercial or financial relationships that could be construedasapotential conflictof interest. Received: 12 August 2014; paper pending published: 24 August 2014; accepted: 21 September2014;publishedonline:14October2014. Citation: CooperDR, BekahDandNadeau JL (2014)Gold nanoparticles and their alternatives for radiation therapy enhancement. Front. Chem. 2:86. doi: 10.3389/ fchem.2014.00086 Thisarticlewas submitted toChemicalEngineering,a sectionof the journalFrontiers inChemistry. Copyright © 2014 Cooper, Bekah andNadeau. This is an open-access article dis- tributedunder the termsof theCreativeCommonsAttributionLicense (CCBY).The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this jour- nal is cited, in accordance with accepted academic practice. No use, distribution or reproduction ispermittedwhichdoesnot complywith these terms. www.frontiersin.org October2014 |Volume2 |Article86 | 60