Seite - 105 - in Critical Issues in Science, Technology and Society Studies - Conference Proceedings of the 17th STS Conference Graz 2018

[4] K. M. Esvelt, A. L. Smidler, F. Catteruccia, and G. M. Church, “Concerning RNA-guided gene drives for the alteration of wild populations,” eLife, vol. 3, Jul. 2014. [5] A. Regalado, “Farmers Seek to Deploy Powerful Gene Drive,” 12-Dec-2017. [6] O. S. Akbari, C.-H. Chen, J. M. Marshall, H. Huang, I. Antoshechkin, and B. A. Hay, “Novel Synthetic Medea Selfish Genetic Elements Drive Population Replacement in Drosophila, and a Theoretical Exploration of Medea-dependent Population Suppression,” ACS Synth Biology, vol. 3, no. 12, pp. 015–928, Dec. 2014. [7] WHO, “World Malaria Report 2016 - Summary.” [8] R. W. Byard, “Lethal Dengue Virus Infection: A Forensic Overview.,” American Journal of Forensic Medecine and Pathology, vol. 37, no. 2, pp. 74–78, Jun. 2016. [9] WHO, “Dengue Control- What is Dengue? URL: http://www.who.int/denguecontrol/disease/ en/,” 06-Jun-2018. [10] R. Galizi et al., “A Synthetic Sex Ratio Distortion System for the Control of the Human Malaria Mosquito,” Nature Communications, vol. 5, p. 3977, Jun. 2014. [11] J. E. DiCarlo, A. Chavez, S. L. Dietz, K. M. Esvelt, and G. M. Church, “Safeguarding CRISPR-Cas9 gene drives in yeast,” Nature biotechnology, vol. 33, no. 12, pp. 1250–1255, Dec. 2015. [12] K. M. Esvelt, “Precaution: Open gene drive research,” Science Letters, vol. 355, no. 6325, pp. 589–590, Feb. 2017. [13] C. Noble, B. Adlam, G. M. Church, K. M. Esvelt, and M. A. Nowak, “Current CRISPR gene drive systems are likely to be highly invasive in wild populations,” eLife, vol. 7, no. e33423, pp. 1–30, Nov. 2017. [14] L. Alphey, “Can CRISPR-Cas9 gene drives curb malaria?,” Nature biotechnology, vol. 34, no. 2, pp. 149–50, Feb. 2016. [15] Gene Watch UK, “Oxitec’s Genetically Modified Mosquitoes: A Credible Approach to Dengue Fever?,” 2015. [16] Gene Watch UK, “Oxitec’s Genetically Modified Mosquitoes: Ongoing Concerns,” 2012. [17] A. F. Harris et al., “Field Performance of Engineered Male Mosquitoes,” Nature Biotechnology, vol. 29, no. 11, pp. 1034–1039, Oct. 2011. [18] C. Rodriguez-Beltran, “GM Mosquitoes: Survival in the Presence of Tetracycline Contamination,” 2012. [19] Y. Nagao and K. Koelle, “Decreases in dengue transmission may act to increase the incidence of dengue hemorrhagic fever,” PNAS, vol. 105, no. 6, pp. 2238–2243, Feb. 2008. [20] H. J. Han et al., “Strain Background Influences Neurotoxicity and Behavioral Abnormalities in Mice Expressing the Tetracycline Transactivator,” Journal of Neuroscience, vol. 32, no. 31, pp. 10574–10586, Aug. 2012. [21] R. Lacroix et al., “Open Field Release of Genetically Engineered Sterile Male Aedes aegypti in Malaysia,” PLOS ONE, vol. 7, no. 8, p. e42771, 2012. 105