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References Barr, S. C., Warner, K. L., Kornreic, B. G., Piscitelli, J., Wolfe, A., Benet, L., & McKerrow, J. H. (2005). A cysteine protease inhibitor protects dogs from cardiac damage during infection by Trypanosoma cruzi. Antimicrobial Agents and Chemotherapy, 49, (12), 5160-5161. Capela, R., Oliveira, R., Gonçalves, L. M., Domingos, A., Gut, J., Rosenthal, P. J., Lopes, F., & Moreira, R. (2009). Artemisinin-dipeptidyl Vinyl Sulfone Hybrid Molecules: Design, Synthesis and Preliminary SAR for Antiplasmodial Activity and Falcipain-2 Inhibition. Bioorganic & Medicinal Chemistry Letters, 19, 3229-3232. Coterón, J. M., Catterick, D., Castro, J., Chaparro, M. J., Díaz, B., Fernández, E., Ferrer, S., Gamo, F. J., Gordo, M., Gut, J., de Las Heras, L., Legac, J., Marco, M., Miguel, J., Muñoz, V., Porras, E., de La Rosa, J. C., Ruiz, J. R., Sandoval, E., Ventosa, P., Rosenthal, P. J., & Fiandor, J. M. (2010). Falcipain Inhibitors: Optimization Studies of the 2-Pyrimidinecarbonitrile Lead Series. Journal of Medicinal Chemistry, 53, 6129–6152. Doyle, P. S., Zhou, Y. M., Engel, J. C., & McKerrow, J. H. (2007). A cysteine protease inhibitor cures Chagas’ disease in an immunodeficient-mouse model of infection. Antimicrobial Agents and Chemotherapy, 51(11), 3932-3939. Dragovich, P. S., Prins, T. J., Zhou, R., Johnson, T. O., Hua, Y., Luu, H. T., Sakata, S. K., Brown, E. L., Maldonado, F. C., Tuntland, T., Lee, C. A., Fuhrman, S. A., Zalman, L. S., Patick, A. K., Matthews, D. A., Wu, E. Y., Guo, M., Borer, B. C., Nayyar, N. K., Moran, T., Chen, L. J., Rejto, P. A., Rose, P. W., Guzman, M. C., Dovalsantos, E. Z., Lee, S., McGee, K., Mohajeri, M., Liese, A., Tao, J. H., Kosa, M. B., Liu, B., Batugo, M. R., Gleeson, J. P. R., Wu, Z. P., Liu, J., Meador, J. W., & Ferre, R. A. (2003). Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics. Journal of Medicinal Chemistry, 46(21), 4572-4585. Ehmke, V., Heindl, C., Rottmann, M., Freymond, C., Schweizer, W. B., Brun, R., Stich, A., Schirmeister, T., & Diederich, F. (2011). Potent and Selective Inhibition of Cysteine Proteases from Plasmodium Falciparum and Trypanosoma Brucei. ChemMedChem, 6, 273–278. Ehmke, V., Quinsaat, J. E. Q., Rivera-Fuentes, P., Heindl, C., Freymond, C., Rottmann, M., Brun, R., Schirmeister, T., & Diederich, F. (2012). Tuning and Predicting Biological Affinity: Aryl Nitriles as Cysteine Protease Inhibitors. Organic & Biomolecular Chemistry, 10, 5764–5768. Ekici, O. D., Li, Z. Z., Campbell, A. J., James, K. E., Asgian, J. L., Mikolajczyk, J., Salvesen, G. S., Ganesan, R., Jelakovic, S., Gruetter, M. G., & Powers, J. C. (2006). Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases- 2, -3, -6, -7, -8, -9, and -10. Journal of Medicinal Chemistry, 49(19), 5728-5749. Engel, J. C., Doyle, P. S., Hsieh, I., & McKerrow, J. H. (1998). Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection. Journal of Experimental Medicine, 188(4), 725- 734. Gibbons, P., Verissimo, E., Araujo, N. C., Barton, V., Nixon, G. L., Amewu, R. K., Chadwick, J., Stocks, P. A., Biagini, G. A., Srivastava, A., Rosenthal, P. J., Gut, J., Guedes, R. C., Moreira, R., Sharma, R., Berry, N., Cristiano, L. S., Shone, A. E., Ward, S. A., & O’Neill, P. M. (2010). Endoperoxide Carbonyl Falcipain 2/3 Inhibitor Hybrids: Toward Combination Chemotherapy of Malaria Through a Single Chemical Entity. Journal of Medicinal Chemistry, 53, 8202-8206. Glória, P. M. C., Coutinho, I., Gonçalves, L. M., Baptista, C., Soares, J., Newton, A. S., Moreira, R., Saraiva, L., & Santos, M. M. M. (2011). Aspartic vinyl sulfones: inhibitors of a caspase-3-
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Biomedical Chemistry: Current Trends and Developments
Title
Biomedical Chemistry: Current Trends and Developments
Author
Nuno Vale
Publisher
De Gruyter Open Ltd
Date
2016
Language
English
License
CC BY-NC-ND 4.0
ISBN
978-3-11-046887-8
Size
21.0 x 29.7 cm
Pages
427
Keywords
Physical Sciences, Engineering and Technology, Chemistry, Organic Chemistry, Green Chemistry
Categories
Naturwissenschaften Chemie
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Biomedical Chemistry: Current Trends and Developments