Page - 79 - in Advances in Neuroimmunology

BrainSci. 2016,6, 16 17. Crews, F.T.; Vetreno,R.P.Neuroimmunebasis of alcoholic braindamage. Int. Rev. Neurobiol. 2014, 118, 315–357. [PubMed] 18. Crews,F.T.;Zou, J.;Qin,L. Inductionof innate immunegenes inbraincreate theneurobiologyofaddiction. BrainBehav. Immun. 2011,25, S4–S12. [CrossRef] [PubMed] 19. Qin,L.;Crews,F.T.Nadphoxidaseandreactiveoxygenspeciescontribute toalcohol-inducedmicroglial activationandneurodegeneration. J.Neuroinflamm. 2012,9, 5. [CrossRef] [PubMed] 20. He,J.;Crews,F.T.IncreasedMCP-1andmicrogliainvariousregionsofthehumanalcoholicbrain.Exp.Neurol. 2008,210, 349–358. [CrossRef] [PubMed] 21. Dennis,C.V.;Sheahan,P.J.;Graeber,M.B.;Sheedy,D.L.;Kril, J.J.; Sutherland,G.T.Microglialproliferation in thebrainofchronicalcoholicswithhepaticencephalopathy.Metab. BrainDis.2014,29, 1027–1039. [CrossRef] [PubMed] 22. Marshall, S.A.;McClain, J.A.; Kelso,M.L.;Hopkins,D.M.; Pauly, J.R.;Nixon,K.Microglial activation is notequivalent toneuroinflammation inalcohol-inducedneurodegeneration: The importanceofmicroglia phenotype.Neurobiol.Dis. 2013,54, 239–251. [CrossRef] [PubMed] 23. Qin, L.;He, J.; Hanes, R.N.; Pluzarev,O.;Hong, J.S.; Crews, F.T. Increased systemic andbrain cytokine productionandneuroinflammationbyendotoxin followingethanol treatment. J.Neuroinflamm. 2008,5, 10. [CrossRef] [PubMed] 24. Zahr,N.M.; Luong,R.; Sullivan,E.V.; Pfefferbaum,A.Measurementof serum, liver, andbrain cytokine induction, thiamine levels, and hepatopathology in rats exposed to a 4-day alcohol binge protocol. AlcoholClin. Exp.Res. 2010,34, 1858–1870. [CrossRef] [PubMed] 25. Tremblay,M.E.; Stevens,B.; Sierra,A.;Wake,H.; Bessis,A.;Nimmerjahn,A.The roleofmicroglia in the healthybrain. J.Neurosci. 2013,31, 16064–16069. [CrossRef] [PubMed] 26. Raivich,G.; Bohatschek,M.;Kloss,C.U.;Werner,A.; Jones,L.L.;Kreutzberg,G.W.Neuroglial activation repertoire in the injuredbrain:Gradedresponse,molecularmechanismsandcues tophysiological function. BrainRes. Rev. 1999,30, 77–105. [CrossRef] 27. Nimmerjahn,A.;Kirchhoff,F.;Helmchen,F.Restingmicroglial cellsarehighlydynamicsurveillantsofbrain parenchyma invivo.Science2005,308, 1314–1318. [CrossRef] [PubMed] 28. Perry,V.H.;Holmes,C.Microglialpriming inneurodegenerativedisease.Nat. Rev.Neurol. 2014,10, 217–224. [CrossRef] [PubMed] 29. Graeber,M.B.;Streit,W.J.Microglia: Biologyandpathology.ActaNeuropathol. 2009,119, 89–105. [CrossRef] [PubMed] 30. Ward,R.J.;Colivicchi,M.A.;Allen,R.; Schol,F.;Lallemand,F.;deWitte,P.;Ballini,C.;Corte,L.D.;Dexter,D. Neuro-inflammation induced in thehippocampusof ‘bingedrinking’ ratsmaybemediatedbyelevated extracellularglutamatecontent. J.Neurochem. 2009,111, 1119–1128. [CrossRef] [PubMed] 31. McClain, J.A.;Morris, S.A.;Deeny,M.A.;Marshall, S.A.;Hayes,D.M.;Kiser,Z.M.;Nixon,K.Adolescent bingealcoholexposure induces long-lastingpartialactivationofmicroglia.BrainBehav. Immun. 2011,25, S120–S128. [CrossRef] [PubMed] 32. Bilbo, S.D.; Schwarz, J.M.Early-lifeprogrammingof later-life brainandbehavior: Acritical role for the immunesystem.Front. Behav.Neurosci. 2009,3, 14. [CrossRef] [PubMed] 33. Ramaglia,V.;Hughes,T.R.;Donev,R.M.;Ruseva,M.M.;Wu,X.;Huitinga, I.;Baas,F.;Neal, J.W.;Morgan,B.P. C3-dependentmechanismofmicroglialprimingrelevant tomultiplesclerosis.Proc.Natl. Acad. Sci.USA 2012,109, 965–970. [CrossRef] [PubMed] 34. Qin, L.; Crews, F.T. Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration. J.Neuroinflamm. 2012,9, 130. [CrossRef] [PubMed] 35. Qin, L.; Liu, Y.; Hong, J.S.; Crews, F.T.Nadphoxidase and agingdrivemicroglial activation, oxidative stress, anddopaminergicneurodegenerationfollowingsystemicLPSadministration.Glia2013,61, 855–868. [CrossRef] [PubMed] 36. Harford,T.C.;Grant,B.F.;Yi,H.Y.;Chen,C.M.PatternsofDSM-IValcoholabuseanddependencecriteria amongadolescentsandadults: Results fromthe2001nationalhouseholdsurveyondrugabuse.AlcoholClin. Exp.Res. 2005,29, 810–828. [CrossRef] [PubMed] 37. White,A.M.;Kraus,C.L.; Swartzwelder,H.Manycollege freshmendrinkat levels farbeyond thebinge threshold.AlcoholClin. Exp.Res. 2006,30, 1006–1010. [CrossRef] [PubMed] 79