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Received:24April2014;accepted:24 June2014;publishedonline:15 July2014. Citation: Conde J, Dias JT, Grazú V,MorosM, Baptista PV and de la Fuente JM (2014)Revisiting 30 years of biofunctionalizationand surface chemistry of inorganic nanoparticles fornanomedicine.Front.Chem.2:48.doi:10.3389/fchem.2014.00048 Thisarticlewas submitted toChemicalEngineering,a sectionof the journalFrontiers inChemistry. Copyright © 2014 Conde,Dias,Grazú,Moros,Baptistaandde laFuente.This is an open-access article distributedunder the terms of theCreativeCommonsAttribution License (CCBY).Theuse, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are creditedand that the original publica- tion in this journal is cited, in accordance with accepted academic practice. No use, distributionor reproduction ispermittedwhichdoesnot complywith these terms. www.frontiersin.org July2014 |Volume2 |Article48 | 34